The Call of the Wild is a vibrant story of Buck, a big and kindhearted dog, a crossbreed between a St. Bernard and a Scotch Collie, whose carefree life of leisure was suddenly upset when he was stolen from his home in Santa Clara County, California and deported up north, to be sold in Skagway, Alaska, and taken further north, to Dawson City, Yukon, during the late 1890s Klondike Gold Rush, when strong sled dogs were in high demand.
As a newcomer to the dog team delivery service - and not before long their front-runner - Buck, a dog like no other, who had been spoiled, and who had suffered, but he could not be broken, is having the time of his life. Forced to fight to survive, eventually taken by his last owner, John Thornton, to proximity of the Arctic Circle, somewhere between Yukon and Alaska, he progressively depends on his primal instincts, sheds the comforts of civilization and responds to "the call of the wild", as master of his own.
With Dr. John Watson about to marry and end their partnership, a disconsolate Sherlock Holmes occupies his time investigating the schemes of his archenemy, Professor James Moriarty. However, when Moriarty warns that he considers the Watsons a legitimate target for his retaliation against the detective, Holmes must save them and get John involved in one last case.
To do so, they join the Roma lady Madam Simza Heron's quest to find her missing brother, Renee, who may be the key to defeating Moriarty. Together, the trio find themselves involved in a dangerous international conspiracy led by the Napoleon of Crime in which the fate of all of Europe hangs in the balance.
After finally catching serial killer and occult "sorcerer" Lord Blackwood, legendary sleuth Sherlock Holmes and his assistant Dr. Watson can close yet another successful case. But when Blackwood mysteriously returns from the grave and resumes his killing spree, Holmes must take up the hunt once again. Contending with his partner's new fiancée and the dimwitted head of Scotland Yard, the dauntless detective must unravel the clues that will lead him into a twisted web of murder, deceit, and black magic - and the deadly embrace of temptress Irene Adler.